The SEG Plaza, a 291-meter building (not counting the antenna) had vacillated at around 13:50 p.m. local time (05 GMT) on Tuesday, forcing the evacuation of those inside.
Images posted on social media showed several hundred pedestrians running away from the perimeter of the building in the ultra-modern metropolis on the outskirts of Hong Kong.
The 78-story tower is located in a district of central Shenzhen, Futian, known for its gigantic pedestrian thoroughfare lined with shops and malls.
The Shenzhen Emergency Management Office quickly said "no earthquake hit the city."
After inspection, officials of the district added that they had found "no security anomalies in the main structure and the environment of the building" and that its interior and exterior elements did not appear to have been damaged.
The building was no longer shaking when the evacuation was completed, according to Chinese media, and no new movement has been detected since, according to local authorities.
The SEG Plaza, erected in 2000, is the 18th skyscraper in Shenzhen by height, according to the ranking of the Council on Tall Buildings and Urban Habitat.
Five of the tallest skyscrapers in the world are located in China, including the Shanghai Tower, which has 128 floors and stands 632 meters high in the Chinese economic capital.